张丽娜;孔祥兴;李昕琳;梅彦侠;李军;

• 1:浙江大学医学院附属第二医院大肠外科
• 2:浙江大学医学院附属第二医院肿瘤研究所(恶性肿瘤预警与干预教育部重点实验室浙江省医学分子生物学重点实验室)
• 3:中国科学院大学宁波华美医院乳腺外科

摘要(Abstract)：

结直肠癌在国内外均是最常见的恶性肿瘤之一。其治疗策略的选择依赖于TNM分期。目前,T分期在预后预测中的权重正越来越得到重视。在多项研究中,肿瘤侵犯浆膜或邻近脏器(pT4期)被认为与其不良预后相关,且这类患者需要接受更强的辅助化疗。然而,对结直肠癌pT4期的准确诊断是一个全球共性难题,临床实际工作中,存在pT4期诊断不足的可能。基于此,本文将对结直肠癌pT4期诊断的病理学标准及其诊断过程中的难点与原因进行总结,并对目前提升pT4期诊断准确率的辅助方案的研究进展进行综述。

关键词(KeyWords)： 结直肠癌;病理诊断;浆膜浸润

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(81672916);国家自然科学基金重点项目(11932017);; 国家重点研发计划(2017YFC0908200)

作者(Authors): 张丽娜;孔祥兴;李昕琳;梅彦侠;李军;

DOI: 10.13267/j.cnki.syzlzz.2021.002

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