结直肠癌pT4期诊断的难点及辅助诊断方案的研究进展
张丽娜;孔祥兴;李昕琳;梅彦侠;李军;
摘要(Abstract):
结直肠癌在国内外均是最常见的恶性肿瘤之一。其治疗策略的选择依赖于TNM分期。目前,T分期在预后预测中的权重正越来越得到重视。在多项研究中,肿瘤侵犯浆膜或邻近脏器(pT4期)被认为与其不良预后相关,且这类患者需要接受更强的辅助化疗。然而,对结直肠癌pT4期的准确诊断是一个全球共性难题,临床实际工作中,存在pT4期诊断不足的可能。基于此,本文将对结直肠癌pT4期诊断的病理学标准及其诊断过程中的难点与原因进行总结,并对目前提升pT4期诊断准确率的辅助方案的研究进展进行综述。
关键词(KeyWords): 结直肠癌;病理诊断;浆膜浸润
基金项目(Foundation): 国家自然科学基金(81672916);国家自然科学基金重点项目(11932017);; 国家重点研发计划(2017YFC0908200)
作者(Authors): 张丽娜;孔祥兴;李昕琳;梅彦侠;李军;
DOI: 10.13267/j.cnki.syzlzz.2021.002
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