莱菔硫烷应用于肿瘤治疗的机制研究
王玉金;白明悦;田颖;陈文明;
摘要(Abstract):
莱菔硫烷(sulforaphane,SFN)是1种异硫氰酸盐。SFN是已知的异硫氰酸盐类物质中抗癌活性最强的1种。SFN相对分子质量为177.3,化学式简写作1-异硫氰基-4-(甲基亚硫酰基)丁烷[1-isothiocyanato-4-(methylsulfinyl)butane],分子式为C_6H_(11)S_2NO。莱菔硫烷不仅可以提高机体的抗氧化能力,还可以抑制并杀死肿瘤细胞,是蔬菜中所发现的抗癌效果最好的植物活性物质。在中西医结合的研究基础之上,本文详细论述近2年来莱菔硫烷的抗肿瘤机制的研究进展,探讨莱菔硫烷在肿瘤治疗上的可行性,以期为肿瘤的临床研究及治疗提供新的思路。
关键词(KeyWords): 肿瘤;莱菔硫烷;治疗
基金项目(Foundation): 2019年首都医科大学临床科研创新项目(XSKY2019184)
作者(Authors): 王玉金;白明悦;田颖;陈文明;
DOI: 10.13267/j.cnki.syzlzz.2021.018
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